Controllable mineral coatings on PCL scaffolds as carriers for growth factor release

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mineral coatings modulate β-TCP stability and enable growth factor binding and release.

β-Tricalcium phosphate (β-TCP) is an attractive ceramic for bone tissue repair because of its similar composition to bone mineral and its osteoconductivity. However, compared with other ceramics β-TCP has a rapid and uncontrolled rate of degradation. In the current study β-TCP granules were mineral coated with the aim of influencing the dissolution rate of β-TCP, and also to use the coating as ...

متن کامل

PCL/PHBV Microparticles as Innovative Carriers for Oral Controlled Release of Manidipine Dihydrochloride

Microparticles of poly(ε-caprolactone) (PCL) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) containing manidipine dihydrochloride (MAN) were successfully prepared by the simple emulsion/solvent evaporation method. All formulations showed loading efficiency rates greater than 80% and average particle size less than 8 μm. Formulations had spherical shape with smooth and porous surface fo...

متن کامل

Novel polymeric scaffolds using protein microbubbles as porogen and growth factor carriers.

Polymeric tissue engineering scaffolds prepared by conventional techniques like salt leaching and phase separation are greatly limited by their poor biomolecule-delivery abilities. Conventional methods of incorporation of various growth factors, proteins, and/or peptides on or in scaffold materials via different crosslinking and conjugation techniques are often tedious and may affect scaffold's...

متن کامل

Magnetic Nanoporous Silica as Carriers for Ibuprofen: Adsorption and Release Study

A carrier system based on nanoporous silica (SBA-15) with magnetic nanoparticles of CoFe2O4 was synthesized via the impregnation of cobalt salt, iron salt and citric acid with as-synthesized SBA-15. The obtained samples were characterized by small angle X-ray scattering (SAXS), N2 adsorption/desorption, scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and ultraviolet (UV)...

متن کامل

Cyclodextrins as Sustained-Release Carriers

cyclodextrins (CDs) is a practical and economical way to improve the physicochemical and pharmaceutical properties of administered drug molecules. CDs can improve properties such as solubility, stability, and bioavailability of various drugs, thereby potentially serving as novel drug carriers. In addition, the hydrophobic and ionizable derivatives of CDs are being tested for use in the preparat...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biomaterials

سال: 2012

ISSN: 0142-9612

DOI: 10.1016/j.biomaterials.2011.09.095